List of projects led by Dr. Laila Anjuman Banu at Genomic Research Laboratory, Department of Anatomy, BSMMU
Infectious disease
- SARS-CoV-2 genome sequencing, variant identification, and the association between mutation profile and disease severity in adult Bangladeshi COVID-19 patients
- Phylogenetic analysis of the SARS-CoV-2 variants in COVID-19 adult Bangladeshi patients
- Dengue virus genome sequencing, variant identification
Cardio-genetics
- Whole gene sequencing of the MYH7 and MYBPC3 gene in adult Bangladeshi hypertrophic cardiomyopathy patients
- Genetic analysis of TNNT2 gene in adult Bengali Bangladeshi hypertrophic cardiomyopathy patients
- Genetic analysis of TTN gene in adult Bengali Bangladeshi hypertrophic cardiomyopathy patients
- Genetic analysis of TNN13 gene in adult Bengali Bangladeshi hypertrophic cardiomyopathy patients
- Screening variants in beta-myosin heavy chain genes (6-MHC) in selected dilated cardiomyopathy (DCM) patients in the Bengali population of Bangladesh
- Association between gene polymorphism and essential hypertension in Bangladeshi population
Cancer
- Genetic analysis of BRCAI gene from blood sample in adult Bengali Bangladeshi female with breast cancer
- Genetic analysis of BRCAI gene from breast cancer tissue sample in adult Bengali Bangladeshi female with breast cancer
- Quantitative expression of BRCAI mRNA in adult Bengali Bangladeshi female with breast cancer
- Quantitative expression of BRCA2 mRNA in adult Bengali Bangladeshi female with breast cancer
- Quantitative expression of BARDI gene in adult Bengali Bangladeshi female with breast cancer
- Breast and ovarian cancer gene panel analysis in adult Bengali Bangladeshi female with ovarian cancer
- Association of BRCAI mutations and serum Ca125 and ß-hCG levels in Bengali Bangladeshi ovarian cancer patients
- Genetic analysis of NPM1, FLT3, GATA2, CEBPA genes mutation in adult Bengali Bangladeshi Acute Myeloid Leukemia patients
Metagenomics study on gut microbiome
- Characterization of the gut microbiome of selected female breast cancer patients: A 16s metagenomics study
- Characterization of the gut microbiome of selected diabetes mellitus patients: A 16s metagenomics study
- Characterization of the gut microbiome of selected fatty liver disease patients: A 16s metagenomics study
Kidney disease
- Analysis of HNFI and PAX2 gene mutations to identify hotspots, disease penetrance among congenital kidney and urinary tract disease patients of Bangladesh
- Genetic analysis of PKDI gene in autosomal dominant polycystic kidney disease patient
- Pedigree analysis of polycystic kidney disease patient
Thyroid disease
- Genetic analysis of Thyroid Transcription Factor 2 gene in congenital hypothyroidism patient
- Genetic analysis of NKX2.5 gene in Bangladeshi pediatric patients with congenital hypothyroidism
Others
- Genetics of infertility
- Expression profiling of Myeloperoxidase mRNA in neutrophils of Bangladeshi children with polyarticular and enthesitis related juvenile idiopathic arthritis
- Detection of clinically relevant copy number variation ofSEZ6/2 gene in a Bangladeshi population